世界主要貨運航空樞紐(World Major Cargo Airline Hubs)-2022

 世界的客運航空公司有不少除了載人之外，也兼營載貨的業務，受到2020年之後的疫情影響，多數載客的航空公司也將部分客機改成專職載貨，當然也有純粹只是運貨的貨運航空公司。以下是世界貨運量比較大的貨運航空公司以及比較知名的貨運航空列表，同時也列出主要樞紐與次要樞紐貨運機場。

航空公司	IATA 代碼	主要樞紐	次要樞紐	備註
Federal Express	FX	SuperHub Memphis Asia Pacific Guangzhou Osaka–Kansai Seoul–Incheon Shanghai–Pudong Singapore Canada Toronto–Pearson Central/Southern Europe Milan–Malpensa Central/Western Europe Cologne/Bonn Paris–Charles de Gaulle Liège Middle East Dubai–International United States National Hub Indianapolis Regional Hubs Anchorage Fort Worth–Alliance Greensboro Miami Newark Oakland		Cargo only
United Parcel Service	5X	Worldport Louisville (KY) Asia/Pacific Hong Kong Kuala Lumpur–International Shanghai–Pudong Shenzhen Canada Hamilton (ON) Europe Cologne/Bonn East Midlands (England) United States Anchorage Columbia (SC) Chicago–Rockford Dallas/Fort Worth Ontario (CA) Miami Philadelphia		Cargo only
Qatar Airline Cargo	QR	Hamad International Airport
Emirates SkyCargo	EK	Al Maktoum International Airport
Cathay Pacific Cargo	CX	Hong Kong
Korean Air Cargo	KE	Gimpo International Airport Incheon International Airport	Focus City Gimhae International Airport Jeju International Airport
Luthansa Cargo	LH	Frankfurt Airport
Cargolux	CV	Luxembourg Airport Zhengzhou Xinzheng International Airport		Cargo only
Turkish Cargo	TK	Istanbul Airport
China Southern Airline Cargo	CZ	Beijing–Daxing Guangzhou	Chongqing Shanghai–Pudong Shenzhen Ürümqi Focus City Bangkok–Suvarnabhumi Changchun Chengdu–Shuangliu Changsha Dalian Guiyang Haikou Hangzhou Harbin Seoul–Incheon Jieyang Kunming Sanya Shenyang Wuhan Xi'an Zhengzhou Zhuhai
Air China	CA	Beijing–Capital Beijing–Daxing Chengdu–Shuangliu	Shanghai–Pudong Focus City Chongqing Dalian Hangzhou Hohhot Kunming Shenzhen Tianjin Wuhan
Singapore Airlines	SQ	Changi Airport
China Airlines	CI	Taipei–Taoyuan	Hong Kong Kaohsiung Taipei–Songshan
AirBridgeCargo Airlines	RU	Sheremetyevo International Airport Krasnoyarsk International Airport		Cargo only
United Airlines	UA	Chicago–O'Hare Denver Guam Houston–Intercontinental Los Angeles Newark San Francisco Washington–Dulles
Atlas Air	5Y	Anchorage Chicago–O'Hare Cincinnati Los Angeles Miami New York–JFK Everett Huntsville		Cargo only
All Nippon Airways	NH	Tokyo–Haneda Tokyo–Narita	Osaka–Itami Osaka–Kansai Focus City Fukuoka Nagoya–Centrair Naha/Okinawa Sapporo–Chitose
British Airways	BA	London–Heathrow London–Gatwick
Polar Air Cargo	PO	Anchorage Cincinnati Los Angeles Hong Kong Seoul-Incheon Tokyo-Narita	Chicago-O'Hare New York-JFK Miami Nagoya-Centrair
Air France	AF	Paris–Charles de Gaulle Paris–Orly	Focus City Bordeaux Lyon Marseille Nice Toulouse
American Airlines	AA	Charlotte Chicago–O’Hare Dallas/Fort Worth Los Angeles Miami New York–JFK New York–LaGuardia Philadelphia Phoenix–Sky Harbor Washington–National
KLM	KL	Amsterdam Airport Schiphol
Kalitta Air	K4	Anchorage Leipzig/Halle Cincinnati Hong Kong New York-JFK Los Angeles
AeroLogic	3S	Leipzig/Halle Airport Frankfurt Airport		Cargo only
Asiana Airlines	OZ	Gimpo International Airport Incheon International Airport	Gimhae International Airport Jeju International Airport	Cargo only
DHL Aviation	ES	Bangalore Cincinnati Hong Kong Leipzig/Halle East Midlands Airport		Cargo only
EVA Air Cargo	BR	Taipei–Taoyuan Bangkok–Suvarnabhumi Hong Kong Kaohsiung Taipei–Songshan London Vienna Brussels Los Angeles Dallas/Fort Worth Chicago Atlanta New York
Antonov Airlines	N.A.	Hostomel Airport		Cargo only
SF Airlines	O3	Shenzhen Bao'an International Airport		Cargo only
China Cargo Airlines (China Eastern Airlines)	CK	Shanghai Pudong International Airport		Cargo only